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Malignancy of the anus

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The anus is the end of the large intestine , below the rectum , through which stool solid waste leaves the body. The anus is formed partly from the outer skin layers of the body and partly from the intestine. Two ring-like muscles, called sphincter muscles, open and close the anal opening and let stool pass out of the body. Enlarge Anatomy of the lower gastrointestinal digestive system showing the colon, rectum, and anus. Other organs that make up the digestive system are also shown.
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What Is Anal Cancer?

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Cancers Associated with Human Papillomavirus (HPV) | CDC

Anal cancer is a cancer which arises from the anus , the distal opening of the gastrointestinal tract. Prevention includes avoiding risk factors and HPV vaccination. Symptoms of anal cancer can include pain or pressure in the anus or rectum, a change in bowel habits, a lump near the anus, rectal bleeding, itching or discharge. Bleeding may be severe. Most anal cancers are squamous cell carcinomas epidermoid carcinomas , that arises near the squamocolumnar junction. It may be keratinizing basaloid or non-keratinizing cloacogenic.
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Cancer of the anus

Some of the signs and symptoms of anal cancer are non-specific and are similar to other less serious conditions. Cancer of the anus is considered rare when compared to other forms of cancer. It's estimated that 0. The anus is at the end of the digestive tract. It is a collection of muscles that form a ring and is about 4 to 5 centimeters about 1.
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Colorectal cancer is one of the most common types of cancer in the world 1. In , colorectal cancer was the leading cause of cancer-associated mortality in Japanese women and the third leading cause in Japanese men 2. The biology of colorectal carcinoma may differ by location and it remains unclear whether carcinoma of the colon caecum to sigmoid and rectum should be considered as a single entity or as two distinct entities 3.
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